DIVISION OF NEUROPATHOLOGY
UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE
DEPARTMENT OF PATHOLOGY
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Division of Neuropathology University of Pittsburgh School of Medicine Room A506 PUH 200 Lothrop Street Pittsburgh, PA 15213 Tel: 412-647-9417 |
NEUROPATHOLOGY TRAINING MANUAL
Educational Objectives
Hypoxia / Ischemia Adult and Pediatric
- Know the role of glucose and creatine phosphate in cerebral metabolism under aerobic and anaerobic conditions.
- Know the definition of and distinction between: hypoxia, anoxia, ischemia and infarction.
- Know the morphologic correlates of ischemia, infarction.
- Know the consequences of cerebral ischemia on blood-brain-barrier.
- Know the relationship between hypoglycemia and cerebral ischemia.
- Know the pathophysiologic basis of cerebral autoregulation.
- Know the anatomic and physiologic basis of selective vulnerability and how it differs in adult brain and premature brain.
- Know how to recognize and distinguish ulegyria, multicystic encephalopathy and hydranancephaly.
- Know the pathogenesis of laminar cortical necrosis and arterial border zone infarcts.
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