DIVISION OF NEUROPATHOLOGY

UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE
DEPARTMENT OF PATHOLOGY

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Division of Neuropathology
University of Pittsburgh
School of Medicine
Room A506 PUH
200 Lothrop Street
Pittsburgh, PA 15213
Tel: 412-647-9417

NEUROPATHOLOGY TRAINING MANUAL

Educational Objectives
Neuroanatomy / Histology

  1. Know the major morphological, ultrastructural, and immunohistochemical characteristics of the different neuroectodermal and mesenchymal cellular constituents of the nervous system.
  2. Know the histologic and cytologic structure of the specialized regional organs of the nervous system: the pineal gland, pituitary gland, circumventricular organs, optic nerves, olfactory tracts and bulbs, and filum terminale.
  3. Know the principal reactions shown by each nervous system cell type to aging, disease, and neoplastic transformation.
  4. Know the appropriate use of special histochemical and immunohistochemical stains.
  5. Know the major levels of the nervous system and the signs and symptoms produced by lesions at these different levels. Know the difference between an intra-axial versus an extra-axial lesion.
  6. Know how to distinguish between a lesion of the peripheral and central nervous system using clinical information.
  7. Know how to distinguish extradural, intradural extramedullary, and intramedullary spinal cord process, and the implications of this distinction.
  8. Know the anatomical basis of visual field abnormalities.
  9. Know the major motor, sensory, and cognitive consequences of lesions of the frontal, parietal, occipital, temporal, and limbic lobes.
Path Department