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NEUROPATHOLOGY TRAINING MANUAL
Educational Objectives
Neuroanatomy / Histology
- Know the major morphological, ultrastructural, and immunohistochemical characteristics of the different neuroectodermal and mesenchymal cellular constituents of the nervous system.
- Know the histologic and cytologic structure of the specialized regional organs of the nervous system: the pineal gland, pituitary gland, circumventricular organs, optic nerves, olfactory tracts and bulbs, and filum terminale.
- Know the principal reactions shown by each nervous system cell type to aging, disease, and neoplastic transformation.
- Know the appropriate use of special histochemical and immunohistochemical stains.
- Know the major levels of the nervous system and the signs and symptoms produced by lesions at these different levels. Know the difference between an intra-axial versus an extra-axial lesion.
- Know how to distinguish between a lesion of the peripheral and central nervous system using clinical information.
- Know how to distinguish extradural, intradural extramedullary, and intramedullary spinal cord process, and the implications of this distinction.
- Know the anatomical basis of visual field abnormalities.
- Know the major motor, sensory, and cognitive consequences of lesions of the frontal, parietal, occipital, temporal, and limbic lobes.
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