DIVISION OF NEUROPATHOLOGY
UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE
DEPARTMENT OF PATHOLOGY
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Division of Neuropathology University of Pittsburgh School of Medicine Room A506 PUH 200 Lothrop Street Pittsburgh, PA 15213 Tel: 412-647-9417 |
NEUROPATHOLOGY TRAINING MANUAL
Educational Objectives
Neurodegenerative Diseases
- Know the basic clinical history and gross appearance of the brain in Alzheimer's Disease (AD)
- Know the standard sections taken and stains required for assessment of AD and other dementias.
- Know the criteria for CERAD, NIA-RI and Braak evaluation of AD
- Know the relationship of AD and Dementia with Lewy Bodies (DLB) and the DLB scoring system
- Know the differential diagnosis of fronto-temporal dementias
- Know the differential diagnosis of Parkinsonism
- Know the differential diagnosis for neurodegenerative diseases characterized by aggregation of tau (tauopathies)
- Know the differential diagnosis for neurodegenerative diseases characterized by aggregation of alpha-synuclein (alpha-synucleinopathies)
- Know the basic clinical history, gross appearance and microscopic findings of Parkinson's Disease, amyotrophic lateral sclerosis, Huntington's Disease and Progressive Supranuclear Palsy
- Know the major prion protein disorders including clinical history, gross and microscopic appearance, and special handling precautions for Creutzfeldt-Jakob Disease
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