DIVISION OF NEUROPATHOLOGY
UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE
DEPARTMENT OF PATHOLOGY
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Division of Neuropathology University of Pittsburgh School of Medicine Room A506 PUH 200 Lothrop Street Pittsburgh, PA 15213 Tel: 412-647-9417 |
NEUROPATHOLOGY TRAINING MANUAL
Educational Objectives
Disease of Muscle and Peripheral Nerve
- Know the rationale for performing and the technique for processing skeletal and peripheral nerve biopsies
- Know the algorithm for microscopic analysis of skeletal muscle and peripheral nerve biopsy including paraffin, frozen, teased fiber and EM
- Know what is relevant and important clinical history for evaluating peripheral nerve and muscle biopsies
- Know the differential diagnosis of major histopathological findings in neuromuscular disease (e.g. mitochondrial, congential, toxic neuropathies and myopathies and dystrophin related myopathies)
- Know how to distinguish primary from secondary demyelination
- Know how to recognize the histopathologic features of vasculitis and the clinical implications of this diagnosis
- Know how to recognize the histopathologic features of major peripheral neuropathies.
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