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NEUROPATHOLOGY TRAINING MANUAL
Educational Objectives
Ophthalmic Pathology
- Know how to identify, orient, and systematically examine enucleation specimens, with emphasis on selecting appropriate plane of section for neoplastic, traumatic/forensic, and phthisical eyes.
- Know the importance of clinician-pathologist and pathologist-histotechnician communication, particularly with regard to achieving proper orientation of corneal and conjunctival biopsies.
- Knows normal appearance of ocular structures submitted to pathology.
- Know how to distinguish common pathologic responses in the eye that disrupt visual function from incidental age-related changes.
- Know how to identify diagnostic features of Fuchs dystrophy and keratoconus.
- Knows how to discuss endothelial, inflammatory, and pressure-related causes of bullous keratopathy.
- Knows how to differentiate artifactual from true retinal detachment.
- Know natural history of ocular vs. conjunctival melanomas.
- Know how to evaluate and report pigmented lesions of the eye with an understanding of the pertinent prognostic issues.
- Know the most pertinent margin to examine in retinoblastoma enucleations, and be able to list common clinical mimics
- Know how to recognize pathologic sequelae of diabetes, end-stage glaucoma, and penetrating/perforating trauma.
- Knows how to list the characteristic anterior segment, posterior segment, and optic nerve lesions associated with child/infant abuse, and to discuss non-traumatic medical conditions (if any) that can lead to similar findings.
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